AB1475 DOES VEIN WALL THICKNESS HAVE PROGNOSTIC VALUE IN BEHÇET’S DISEASE? A PROSPECTIVE FOLLOW-UP STUDY

Background We reported the first controlled doppler ultrasound study showing increased common femoral vein (CFV) thickness in Behçet’s Disease (BD). [1] also recently showed that CFV is a distinctive feature of BD, rarely present other inflammatory or vascular diseases with specificity higher than 80% for cut-off value ≥ 0.5 mm. 2 However, association between and any organ involvement, disease course treatment during has not been demonstrated so far. Objectives This aimed to assess longitudinal prognostic measurement prospective follow-up BD patients. Methods In this study, we included 195 patients diagnosis BD. The clinical, demographic, data biomarkers were recorded routine visits. Bilateral was measured ultrasonography by an experienced radiologist at same day. Patients started follow up prospectively 3-6 months intervals urgent visit. Results At baseline, 98.6% had wall above ≥0.5 baseline last clinical characteristics shown Table 1. 139 mean 26.5 (16.9) months. New major involvement relapse leading change seen 39 (28%) Among 22 (15.8%) new 12 vascular, seven ocular, two neurologic one gastrointestinal involvement. 36 only mucocutaneous developed 9 follow-up. These nine thicknesses compared without however reaching significance (0.83 mm vs 0.73 right CFV, 0.80 left CFV: p >0.05 both) 47 patients, second done 19.8 after There no statistically significant difference measurements both CFVs (First vs. 0.79 0.76 mm, p=0.26; 0.75 p=0.26). did find modality, relapses. Conclusion which non-invasive diagnostic tool does show over time our preliminary results suggest may have risk development long term cohort patient numbers would clarify Disclosures None. References [1]Alibaz-Oner F Clin Rheumatol 2019 [2]Alibaz-Oner F. Rheumatology (Oxford). 2021 Disease. Baseline (n=139) Last Follow-up Relapses Involvement Age (SD) 34.85 (8.27) Gender F/M ratio 43/96 Right Wall Thickness 0.791 (0.253) Left 0.797 (0.207) Oral aftous ulcers n (%) 134 (95) 13 (9.4) Genital 84 (60.4) 89 (64.5) 6 (4.3) Eritema Nodosum 62 (44.6) 69 (49.6) (6.5) Arthritis 48 (34.5) 10 (7.2) Major Organ (% ) Vascular 96 (69.1) 35 (25.2) Deep Venous Thrombosis 61 (43.9) 65 (46.8) Pulmonary trombosis 52 (37.4) 23 (16.5) Sinus (8.6) 14 (9.9) (1.4) Trombofilebitis 4 (2.9) 5 (3.6) Neuro-Behcet 16 (11.5) Uveitis 33 (23.7) 40 (28.8) 7 (5) Entero-Behcet 8 (5.8) 1 (0.7) Acknowledgements: NIL. Disclosure Interests None Declared.